A synthetic peptide for use as a blocking control in assays to test for specificity of MARCKS antibody, Alternative Names: MARCKS control peptide, MARCKS antibody Blocking Peptide, Anti-MARCKS Blocking Peptide, myristoylated alanine-rich protein kinase C substrate Blocking Peptide, 80K-L Blocking Peptide, FLJ14368 Blocking Peptide, FLJ90045 Blocking Peptide, MACS Blocking Peptide, PKCSL Blocking Peptide, PRKCSL Blocking Peptide
MARCKS
Reactivité: Humain, Poulet, Boeuf (Vache), Souris, Rat, Poisson zèbre (Danio rerio)
Hôte: Synthetic
BP
Indications d'application
Optimal conditions should be determined by the investigator
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Conseil sur la manipulation
Avoid repeated freeze/thaw cycles.
Stock
-20 °C
Stockage commentaire
Store at -20 °C long term.
Antigène
MARCKS
(Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS))
Sujet
The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.